Preheat oven to 400°. Add panko, cheese and Italian seasoning to a large bowl. Season with salt and pepper. Then mix everything together until thoroughly combined.
Dip cauliflower pieces in egg and then roll in bread crumb mixture until fully coated and place on a baking sheet lined with parchment paper. You may need to press on the coating to help get it to stick to the cauliflower bites. Repeat until all cauliflower is coated.
Bake for about 20-25 minutes, or until coating is golden brown and crunchy. Serve with marinara sauce.